Parenchymal Organ, and Not Splenic, Immunity Correlates with Host Survival during Disseminated Candidiasis
نویسندگان
چکیده
منابع مشابه
Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis.
We examined the relationship between host survival and renal and splenic immune responses in a murine model of hematogenously disseminated candidiasis. Male BALB/c mice were infected via tail vein injection with wild-type C. albicans or with an isogenic, Deltaefg1/Deltaefg1 hypha-deficient mutant. Host survival, organ fungal burden, intracellular cytokine content of splenic and kidney lymphocyt...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2003
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.71.10.5756-5764.2003